Engineering Polymer Networks using a Few Good Reactions
Mon, Mar 31
2:00 PM — 3:15 PM
Steinman Hall 160 - Lecture Hall
The ChE Department would like to welcome Chris Kloxin from the University of DelawareAbstract:
The ‘click’ chemistry paradigm began early last decade as a call to focus on new drug and therapeutic discovery via a “few good reactions.” Click reactions recently have proven useful in a number of fields and are ideally suited for materials synthesis and modification as they are high yielding, selective, modular in nature, and requiring little to no purification. The click chemical concept provides a framework of reactions that essentially break down the barriers between materials synthesis and materials design. In this seminar, I will present the concept of click reactions toward engineering new materials with unique properties for a number of applications, from 3D printing to adhesives. In particular, we will explore the tremendous potential of photo-enabling these reactions to enable scientists and engineers for spatiotemporal control over materials fabrication, modification, and functionalization. Specifically, I will present several new photo-induced click reactions in polymers, including the photo-induced copper catalyzed azide–alkyne cycloaddition (photoCuAAC), thiol–yne photo-coupling and polymerization, and the thiol-Michael polymerization via a photocaged primary amine. I will discuss several specific examples of how we have used these reactions to create and manipulate polymer networks and their properties. Such materials represent dynamic yet robust macromolecular architectures that can adapt to their chemical and physical environment.
Christopher Kloxin is an Assistant Professor in the Departments of Materials Science and Engineering and Chemical and Biomolecular Engineering at the University of Delaware. His research efforts have focused on new photo-initiated click reaction schemes as well as the creation and characterization of covalent adaptable networks. In 2011, he began at the University of Delaware, where his research group utilizes a combination of click and reversible chemical motifs for the design and synthesis of nature-inspired polymeric materials.