All laboratories which use chemicals are required to abide by the standards set by the Occupational Safety and Health Administration (OSHA) in the Code of Federal Regulations (CFR 1910.1450), Occupational Exposure to Hazardous Chemicals in Laboratories; commonly known as the "Laboratory Safety Standard".  EHOS has developed a Chemical Hygiene Plan to give PIs and lab supervisors directions for complying with this regulation, but the manual is not intended to provide a review of the details of the regulation -- for details see Laboratory Safety Standard.